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How to use Clexane correctly

Clexane is a biological drug that is composed of complex processes of living cells or biological material. Its raw material is a molecule called heparin which is itself extracted  from the intestinal mucosa of pigs.  

As you will have understood, Clexane is administered by injection with a syringe. You will find the details of the syringe on the image below.   

Details :   

  • The syringe is color coded by dosage. In this case, the yellow label represents 40mg of product.  
  • The needle is completely covered by a safety sleeve at the end of the injection.  
  • A Datamatrix code is present on each syringe. This one informs on the name, dosage, batch number and date of prescription.  
  • When the plunger is fully depressed, there is an automatic activation of the safety  system of the syringe.    

The manufacture of a syringe is equivalent to 10  months of work and goes  through 74 quality controls during the testing and production process phases.  

Where to inject the product ?   

  •  In the lower part of the stomach, next to the navel  
  • In the so-called ‘fatty’ tissue, located between the skin and the underlying muscle  
  • Alternate the injections: once on the left, once on the right of the navel  

Tips before the injection :  

  • Wash your hands before starting.  
  • Disinfect the injection area with an alcohol swab.  
  • Do not remove the air bubble in the syringe. Turn the syringe upside down,  needle down, and gently tap the syringe so that the bubble goes back up to the plunger.  

If a drop forms at the end of the needle, do not wipe it off, just shake the syringe.   

Tips while injecting :   

  • Start by creating a skin fold between your thumb and index finger   
  • Then insert the needle vertically into the skin fold   
  • Slowly inject the product by pushing the plunger all the way in  
  • Throughout the injection  until  the  needle  is  gently  withdrawn,  hold  the  fold  between your fingers  
  • At the end of the injection, do not massage, scratch or squeeze the skin  

As a reminder, it is important to follow the duration of treatment prescribed by  your doctor or surgeon. The risk of complication is still present up to 35 days after  an orthopedic surgery.  

Injections should be done once a day. Try to do the injection every day at the same time and alternate between the left and right side of the belly button.

For more practical information on the injection of this product, you will  find  a video in your personal program (exercise tab).

Possible side effects :    

Clexane has already been tested on over 15,000 patients in clinical studies. The most common side effect, observed in 1 or more out of 10 people after surgery, is bleeding. This bleeding can manifest itself as hematoma, bruising in areas outside the injection site, hematoma following an injury, epistaxis (nosebleeds) and gastrointestinal  bleeding. 

At the injection site, it is common to observe such things as : hematoma, pain or  other symptoms such as hemorrhage, hypersensitivity, inflammation, mass or  reaction (not otherwise specified).

Hematoma is the result of repeated local injections. It is the most common complication encountered. Here is a picture of a belly with hematomas at the injection sites. This situation is normal, these hematomas will disappear spontaneously.

IMAGE belly

What to do if you miss an injection ?  

If you miss your injection, take the missed dose as soon as possible. If it is almost time for your next injection, skip the missed injection and continue with your usual schedule.   

What to do with the syringe after the injection ?   

You can throw the syringe away with your regular garbage after use. If your syringe is not equipped with an automatic safety system, it is preferable to collect  your syringes in a resealable container (e.g. glass or plastic bottle or plastic box) and then dispose of it with your household waste.   

What if you don’t want to inject Clexane yourself or if you have trouble with the injection?

In these cases, you can always have a nurse come to your home to inject your anticoagulant.

Updated on April 26, 2021

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